Author Topic: sleep and the brain  (Read 1097 times)

towrite

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sleep and the brain
« on: May 05, 2008, 10:31:55 AM »
Learned something new from my shrink and wanted to share it. There's a new study just finished (not published yet 'cuz it's brand new) investigating sleep meds, sleep cycles, etc. The results show that unless you drop into very deep sleep at night, your hypothalamus does not stop producing adrenaline. When that happens, apparently your body converts that adrenaline to cortisol, which puts extra fat around your middle. This is apparently the explanation behind the theory that people who have a spare tire are more prone to heart attacks. The adrenaline during sleep is a killer. In addition, the lack of deep sleep, the presence of too much adrenaline too much of the time causes shrinking of the hippocampus cells, the seat of short term memory. There are only two sleep meds currently on the market which have the necessary ingredients to rebuild the short term memory cells - Lunesta and Ambien CR - by allowing deep sleep. (This was not a study done by the makers of either.) Apparently widely used sleep meds - Trazadone (which I have taken for several years), Zanax, Restoril, and others in that family, do not replicate the architecture of sleep (I love that phrase - so illustrative - I can just visualize the brain waves and sleep cycles), thus do not produce or allow the really deep, healing sleep. Folks with PTSD are more susceptible to this damage, according to her, b/c of the recurring cycles of nightmares and night sweats.

Just thought I'd share that.
"An unexamined life is a wasted life."
                                  Socrates
Time wounds all heels.

LilyCat

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Re: sleep and the brain
« Reply #1 on: May 05, 2008, 10:38:26 AM »
Hey, towrite,

Very interesting! I'll keep my eyes out for that study. (I work for a large medical publisher.)

I can tell you the bit about gaining weight is correct. Two years ago i was diagnosed with obstructive sleep apnea (I figured I had it, just a matter of getting tested). My sleep doctor said I had the worst case he'd seen in 20 years. They want your oxygen levels to be around 95; mine went down to 20 every night within just 3 hours. And, I never got beyond stage 2 sleep. I hadn't been getting REM sleep for who knows how long.

From the extensive reading I've done, the lack of sleep causes weight gain. They don't fully understand it yet, but they do know that it has a snowballing effect -- all sorts of systems come into play.

I can tell you this -- no matter what I did, losing weight before I got treated was at best extremely difficult, and generally impossible. Now that I have everything straightened out, it's much easier.

My doctor confirmed this. (About the difficulty in losing weight.) So, the study you mention makes a lot of sense.

Ambien is an interesting drug. You should go to youtube and search and watch the videos. Some are pretty funny.

Guess you're going to switch?

towrite

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Re: sleep and the brain
« Reply #2 on: May 05, 2008, 12:30:39 PM »
Yeah, I want to try it when I can afford it. Esp b/c of the sleep architecture re-establishment.

Your story is interesting. Did you work on the sleep first or losing weight first? Or did the weight loss follow the sleep gain?

Kate
"An unexamined life is a wasted life."
                                  Socrates
Time wounds all heels.

LilyCat

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Re: sleep and the brain
« Reply #3 on: May 05, 2008, 03:02:40 PM »
I had to get the sleep straightened out. I felt the benefit immediately (no surprise, since I was so sleep-starved) but it took me really a year to get it really consistent.

Then I started losing weight (with diet and exercise, getting treated for apnea is no cure-all for weight loss! I was hoping. Unfortunately...) fairly easily and with good results.

Then I went on Effexor and gained back the 35 pounds before I realized what was happening. So I went off that, on to Wellbutrin, which is GREAT!, and now I've lost the Effexor weight. So -- exasperated sigh! -- I am now losing what I call "net" weight. Yeah!!! The Wellbutrin is really the final cornerstone of the whole thing, I think.

There are SO many stories and evidence about what the lack of proper sleep does. It affects virtually everything in your body. Everything.

...maybe you needed more time to adjust to the new meds? Get off the old and onto the new?? Just a thought.