Random thoughts popping through my brain as I'm reading various posts. Not sure how they would be perceived. Just sharing from my own personal experience, for what it's worth.
Years ago, I volunteered to be in a double-blind study while having my wisdom teeth removed. This study would involve taking various medications, after the surgery, and studying their effects. (I was still an undergrad psychology student so I understood what double-blind studies entail.) I was also newly-sober at the time and understood that I needed to be responsible to protect my sobriety. I shared with these people, who were involved with the study, about my alcohol and drug history, and stated that even though we won't know which drugs would be given to me, I needed to know what classification of drugs would be involved. I gave them a list of which prescription drugs I had abused in the past during my active addiction, (e.g. benzodiazepines), and emphasized that as a recovering dual addict, (alcohol AND drugs), I could not take any medications that have addictive properties, (e.g. demerol, morphine, phenobarbitol, or other addictive narcotics that are classified as controlled substances). They went back and checked the lists of medications that they were planning on using in the study and determined that they were ALL addictive. As a result, we made a mutual decision that I would not participate in the study. The risk to my sobriety was too great to take that kind of gamble.